Publications 2018
Aengenheister, L.; Keevend, K.; Muoth, C.; Schönenberger, R.; Diener, L.; Wick, P.; Buerki-Thurnherr, T. An advanced human in vitro co-culture model for translocation studies across the placental barrier. Sci. Rep. 2018, 8 (1), 5388 (12 pp.). https://doi.org/10.1038/s41598-018-23410-6
Aengenheister, L.; Dietrich, D.; Sadeghpour, A.; Manser, P.; Diener, L.; Wichser, A.; Karst, U.; Wick, P.; Buerki-Thurnherr, T. Gold nanoparticle distribution in advanced in vitro and ex vivo human placental barrier models. J. Nanobiotechnol. 2018, 16 (1), 79 (16 pp.). https://doi.org/10.1186/s12951-018-0406-6
Aengenheister, L. Risks and opportunities of nanomaterial exposure during pregnancy: from placental uptake and translocation to fetal consequences. Doctoral dissertation, ETH Zurich, Zürich, 2018, 227 p. http://hdl.handle.net/20.500.11850/297999
Barosova, H.; Chortarea, S.; Peikertova, P.; Clift, M. J. D.; Petri-Fink, A.; Kukutschova, J.; Rothen-Rutishauser, B. Biological response of an in vitro human 3D lung cell model exposed to brake wear debris varies based on brake pad formulation. Arch. Toxicol. 2018, 92 (7), 2339-2351. https://doi.org/10.1007/s00204-018-2218-8
Bertero, E.; Hasegawa, M.; Staubli, S.; Pellicer, E.; Herrmann, I. K.; Sort, J.; Michler, J.; Philippe, L. Electrodeposition of amorphous Fe-Cr-Ni stainless steel alloy with high corrosion resistance, low cytotoxicity and soft magnetic properties. Surf. Coat. Technol. 2018, 349, 745-751. https://doi.org/10.1016/j.surfcoat.2018.06.003
Beyeler, S.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Wick, P.; Tschanz, S. A.; von Garnier, C.; Blank, F. Acute effects of multi-walled carbon nanotubes on primary bronchial epithelial cells from COPD patients. Nanotoxicology 2018, 12 (7), 699-711. https://doi.org/10.1080/17435390.2018.1472310
Bohmer, N.; Rippl, A.; May, S.; Walter, A.; Heo, M. B.; Kwak, M.; Roesslein, M.; Song, N. W.; Wick, P.; Hirsch, C. Interference of engineered nanomaterials in flow cytometry: a case study. Colloids Surf. B 2018, 172, 635-645. https://doi.org/10.1016/j.colsurfb.2018.09.021
Buerki-Thurnherr, T.; Schaepper, K.; Aengenheister, L.; Wick, P. Developmental toxicity of nanomaterials. Need for a better understanding of indirect effects. Chem. Res. Toxicol. 2018, 31 (8), 641-642. https://doi.org/10.1021/acs.chemrestox.8b00177
Chortarea, S.; Fytianos, K.; Rodriguez-Lorenzo, L.; Petri-Fink, A.; Rothen-Rutishauser, B. Distribution of polymer-coated gold nanoparticles in a 3D lung model and indication of apoptosis after repeated exposure. Nanomedicine 2018, 13 (10), 1169-1185. https://doi.org/10.2217/nnm-2017-0358
Chortarea, S.; Zerimariam, F.; Barosova, H.; Septiadi, D.; Clift, M. J. D.; Petri-Fink, A.; Rothen-Rutishauser, B. Profibrotic activity of multiwalled carbon nanotubes upon prolonged exposures in different human lung cell types. Appl. In Vitro Toxicol. 2018, 5 (1), 47-61. https://doi.org/10.1089/aivt.2017.0033
Drasler, B.; Kucki, M.; Delhaes, F.; Buerki-Thurnherr, T.; Vanhecke, D.; Korejwo, D.; Chortarea, S.; Barosova, H.; Hirsch, C.; Petri-Fink, A.; et al. Single exposure to aerosolized graphene oxide and graphene nanoplatelets did not initiate an acute biological response in a 3D human lung model. Carbon 2018, 137, 125-135. https://doi.org/10.1016/j.carbon.2018.05.012
Fadeel, B.; Bussy, C.; Merino, S.; Vázquez, E.; Flahaut, E.; Mouchet, F.; Evariste, L.; Gauthier, L.; Koivisto, A. J.; Vogel, U.; et al. Safety assessment of graphene-based materials: focus on human health and the environment. ACS Nano 2018, 12 (11), 10582-10620. https://doi.org/10.1021/acsnano.8b04758
Ghitescu, R. E.; Popa, A. M.; Schipanski, A.; Hirsch, C.; Yazgan, G.; Popa, V. I.; Rossi, R. M.; Maniura-Weber, K.; Fortunato, G. Catechin loaded PLGA submicron-sized fibers reduce levels of reactive oxygen species induced by MWCNT in vitro. Eur. J. Pharm. Biopharm. 2018, 122, 78-86. https://doi.org/10.1016/j.ejpb.2017.10.009
Gubala, V.; Johnston, L. J.; Liu, Z.; Krug, H.; Moore, C. J.; Ober, C. K.; Schwenk, M.; Vert, M. Engineered nanomaterials and human health: Part 1. Preparation, functionalization and characterization (IUPAC Technical Report). Pure Appl. Chem. 2018, 90 (8), 1283-1324. https://doi.org/10.1515/pac-2017-0101
Gubala, V.; Johnston, L. J.; Krug, H.; Moore, C. J.; Ober, C. K.; Schwenk, M.; Vert, M. Engineered nanomaterials and human health: Part 2. Applications and nanotoxicology (IUPAC Technical Report). Pure Appl. Chem. 2018, 90 (8), 1325-1356. https://doi.org/10.1515/pac-2017-0102
Keevend, K.; Panzarasa, G.; Starsich, F. H. L.; Zeltner, M.; Spyrogianni, A.; Tsolaki, E.; Fortunato, G.; Pratsinis, S. E.; Bertazzo, S.; Herrmann, I. K. Facile meltPEGylation of flame-made luminescent Tb3+-doped yttrium oxide particles: hemocompatibility, cellular uptake and comparison to silica. Chem. Commun. 2018, 54 (23), 2914-2917. https://doi.org/10.1039/c7cc09402g
Kucki, M.; Aengenheister, L.; Diener, L.; Rippl, A. V.; Vranic, S.; Newman, L.; Vazquez, E.; Kostarelos, K.; Wick, P.; Buerki-Thurnherr, T. Impact of graphene oxide on human placental trophoblast viability, functionality and barrier integrity. 2D Mater. 2018, 5 (3), 035014 (15 pp.). https://doi.org/10.1088/2053-1583/aab9e2
Lacroix, G.; Koch, W.; Ritter, D.; Gutleb, A. C.; Larsen, S. T.; Loret, T.; Zanetti, F.; Constant, S.; Chortarea, S.; Rothen-Rutishauser, B.; et al. Air–liquid interface in vitro models for respiratory toxicology research: consensus workshop and recommendations. Appl. In Vitro Toxicol. 2018, 4 (2), 91-106. https://doi.org/10.1089/aivt.2017.0034
Lese, I.; Graf, D. A.; Tsai, C.; Taddeo, A.; Matter, M. T.; Constantinescu, M. A.; Herrmann, I. K.; Olariu, R. Bioactive nanoparticle-based formulations increase survival area of perforator flaps in a rat model. PLoS One 2018, 13 (11), e0207802 (19 pp.). https://doi.org/10.1371/journal.pone.0207802
Maguire, C. M.; Rösslein, M.; Wick, P. Characterisation of particles in solution – a perspective on light scattering and comparative technologies. Sci. Technol. Adv. Mater. 2018, 19 (1), 732-745. https://doi.org/10.1080/14686996.2018.1517587
May, S. The effect of different engineered nanomaterials (ENMs) on DNA damage and repair pathways. Doctoral dissertation, Universität Konstanz, Konstanz, 2018, 248 p.
May, S.; Hirsch, C.; Rippl, A.; Bohmer, N.; Kaiser, J. P.; Diener, L.; Wichser, A.; Bürkle, A.; Wick, P. Transient DNA damage following exposure to gold nanoparticles. Nanoscale 2018, 10 (33), 15723-15735. https://doi.org/10.1039/C8NR03612H
Notter, T.; Aengenheister, L.; Weber-Stadlbauer, U.; Naegeli, H.; Wick, P.; Meyer, U.; Buerki-Thurnherr, T. Prenatal exposure to TiO2 nanoparticles in mice causes behavioral deficits with relevance to autism spectrum disorder and beyond. Transl. Psychiatry 2018, 8 (1), 193 (10 pp.). https://doi.org/10.1038/s41398-018-0251-2
Ryabova, A. V.; Keevend, K.; Tsolaki, E.; Bertazzo, S.; Pominova, D. V.; Romanishkin, I. D.; Grachev, P. V.; Makarov, V. I.; Burmistrov, I. A.; Vanetsev, A. S.; et al. Visualization of Nd3+-doped LaF3 nanoparticles for near infrared bioimaging via upconversion luminescence at multiphoton excitation microscopy. Biomed. Photonics 2018, 7 (1), 4-12. https://doi.org/10.24931/2413-9432-2018-7-1
Salmeia, K. A.; Gooneie, A.; Simonetti, P.; Nazir, R.; Kaiser, J. P.; Rippl, A.; Hirsch, C.; Lehner, S.; Rupper, P.; Hufenus, R.; et al. Comprehensive study on flame retardant polyesters from phosphorus additives. Polym. Degrad. Stab. 2018, 155, 22-34. https://doi.org/10.1016/j.polymdegradstab.2018.07.006
Siegrist, S.; Cörek, E.; Detampel, P.; Sandström, J.; Wick, P.; Huwyler, J. Preclinical hazard evaluation strategy for nanomedicines. Nanotoxicology 2018, 13 (1), 73-99. https://doi.org/10.1080/17435390.2018.1505000
Spyrogianni, A.; Tiefenboeck, P.; Starsich, F. H. L.; Keevend, K.; Krumeich, F.; Herrmann, I. K.; Leroux, J. C.; Sotiriou, G. A. Near-UV activated, photostable nanophosphors for in vitro dosimetry and dynamic bioimaging. AICHE J. 2018, 64 (8), 2947-2957. https://doi.org/10.1002/aic.16166
Starsich, F. H. L.; Eberhardt, C.; Keevend, K.; Boss, A.; Hirt, A. M.; Herrmann, I. K.; Pratsinis, S. E. Reduced magnetic coupling in ultrasmall iron oxide T1 MRI contrast agents. ACS Appl. Bio Mater. 2018, 1 (3), 783-791. https://doi.org/10.1021/acsabm.8b00244
Vidmar, J.; Buerki-Thurnherr, T.; Loeschner, K. Comparison of the suitability of alkaline or enzymatic sample pre-treatment for characterization of silver nanoparticles in human tissue by single particle ICP-MS. J. Anal. At. Spectrom. 2018, 33 (5), 752-761. https://doi.org/10.1039/C7JA00402H
Vidmar, J.; Loeschner, K.; Correia, M.; Larsen, E. H.; Manser, P.; Wichser, A.; Boodhia, K.; Al-Ahmady, Z. S.; Ruiz, J.; Astruc, D.; et al. Translocation of silver nanoparticles in the ex vivo human placenta perfusion model characterized by single particle ICP-MS. Nanoscale 2018, 10 (25), 11980-11991. https://doi.org/10.1039/C8NR02096E